Mitragynine and 7-hydroxymitragynine (7-OH) are kratom’s two most important alkaloids — and they’re profoundly different. This is essential reading before trying advanced products.
Mitragynine: the main alkaloid
Mitragynine makes up roughly 60%+ of kratom leaf alkaloids. It’s responsible for classic kratom effects — and notably, your body converts some of it into 7-OH naturally.
7-Hydroxy: the potent minor alkaloid
7-OH occurs in tiny amounts in raw leaf but is estimated to be many times more potent by weight at opioid receptors. Isolated 7-OH products like our new SMAX 100 7OH Tablets deliver precision dosing impossible with leaf — which is exactly why they demand extra respect.
Safety: the critical part
Higher potency means smaller margins. Advanced alkaloid products are for experienced adults 21+ only: start with the lowest serving, never combine with alcohol or sedatives, and heed every label warning. Read our full safety guidance in the FAQ hub.
Which is right for you?
Most people should stick with full-spectrum leaf products — Gold gummies, powder, shots. Curious about the cutting edge? Shop the SMAX Collection — now in stock.